Density of SERT, VGLUT3 and SERT/VGLUT3 axon terminals in immature and mature VGLUT3 WT mice.
Dorsal striatum
Lateral septum
Ventral Hipp
Dorsal Hipp
P15
P60
P15
P60
P15
P60
P15
P60
Surface (μm2)
9612
6855.6
9184.8
10173.4
9754.4
7749.6
8828.8
8965.8
SERT
20.8 ± 2.1
18.6 ± 3.7
15 ± 1.7
26.4 ± 4.5
20.4 ± 3.7
26.7 ± 4.6
15 ± 3.6
22.2 ± 4.6
VGLUT3
77 ± 11.4
42.8 ± 5.2
50.4 ± 9.3
32.8 ± 6.2
24.4 ± 1.4
24 ± 7.08
38.8 ± 6.7
38.8 ± 8.2
SERT/VGLUT3
0.2 ± 0.2**
0⧫
2.8 ± 1.2**
4 ± 1.7⧫
6.8 ± 3.4**
3.7 ± 1.4⧫
3.2 ± 1.4**
3.2 ± 1.2⧫
Mean (± SEM) number of immunoreactive axon terminals per surface of thin sections examined in different brain regions after dual immunolabeling in WT mice at immature (P15) or adult (P60–70) age (n = 5 mice per age). Statistical differences were calculated on the ratio of labeled terminals per examined surface. **p < 0.01 compared to VGLUT3 in P15 mice; ⧫p < 0.05 compared to VGLUT3 in P60 mice.